The Ettan™ IPGphor™ 3 is a fully integrated isoelectric focusing (IEF) system optimized to deliver high throughput, ease of use, speed, reproducibility, and high protein-loading capacity. The instrument boasts a number of key improvements over previous systems, including enhanced electrical and safety features, improved reduction in condensation, and completely redesigned casing and lid to optimize handling of CyDye™ labeled proteins and other light-sensitive samples. Temperature control and general ease of use are all features introduced from regular customer feedback. The PC control software has been updated to improve its ease of use and import/export capabilities.