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MacroCap SP- Strong cation exchanger for PEGylated proteins and other large biomolecules.
- High purity and yield of PEGylated proteins at high sample loads.
- Highly porous base matrix makes extensive surface area available for adsorption of large molecules.
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MacroCap SP
Technical Information
For purification of PEGylated proteins and other large biomolecules.
| TECHNICAL SPECIFICATIONS |
| Composition | Acrylamide-dextran copolymer |
| Media type | Strong cation exchanger, SO3- |
| Particle size | 50 µm |
| Flow rate | 120 cm/h in BPG 300, 20-cm bed height or 70 cm/h in BPG 300, 30-cm bed height using process buffers with the same viscosity as water at < 3 bar (0.3 MPa) |
| Recommended separation range | a) Proteins in excess of 150 000 Mr
b) Functionalized dextrans or PEGs greater than or equal to 20 000 Mr
PEGylated proteins containing greater than or equal to 10 000 Mr of PEG (total) per conjugate. |
| pH stability (operational) | 3-12 |
| CIP stability (short term) | 2-13 |
For technical information, please download the instruction and data file in the Product Related Documents list on the left.
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Product related documents
Application note
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