ÄKTA™ - The purification platform preferred by more than 100 000 scientists worldwide

ÄKTA is a Swedish word that means true, genuine, or real. ÄKTA design is the name for a platform of systems that help you make real advances in biomolecular purification and separation. By more than 100 000 scientists worldwide – purifying proteins for structural or functional studies, developing protocols, and optimizing methods for biomolecule purification – the name ÄKTA has always meant outstanding protein purification. This proud lineage now sky rockets into the next generation with ÄKTA avant. ÄKTA avant is the fastest, most secure means to develop scalable and robust chromatographic processes for biopharmaceutical production.

ÄKTA systems work with intelligent, scalable UNICORN™ software, which makes it simple to control every stage and scale of your purification process. GE Healthcare also offers an extensive range of prepacked columns, chromatography media, and filters to increase productivity and obtain optimal results.

With the ability to purify virtually 100% of all biomolecules, the ÄKTA design platform can handle the simplest and the toughest of challenges. It gives you speed, ease-of-use, and flexibility whatever your purification application or scale. Our interactive
ÄKTA systems selection guide is a practical tool that helps you to select the right system for your purification needs.

ÄKTA systems - Ability to purify virtually 100% of all biomolecules

	ÄKTA™ avant ÄKTA avant 25 is a preparative liquid chromatography system intended for media screening, method scouting, and process development. UNICORN™ 6 control software has been specially developed for ÄKTA avant to increase productivity and efficiency. The ÄKTA avant system offers a complete solution for fast and secure process development. Product and Order Information
	ÄKTAmicro™ ÄKTAmicro system is developed from the ÄKTA design chromatography platform utilizing inert, biocompatible flow paths with minimized dead volumes to limit sample dilution, ensure high sample recovery, top resolution, and high sensitivity during micropurification. The system is also an excellent choice for fast purity analysis by gel filtration in method development and for drug target characterization. Product and Order Information
	ÄKTAxpress™ ÄKTAxpress performs unattended purification of antibodies and affinity tagged proteins and hence saves time in the lab. This system produce highest possible purity of target proteins allowing, for example, structural and functional studies to be easily performed up-stream. Optimized protocols with a choice of up to four different purification steps makes it easy to use with minimial or no need for chromatography expertise. Product and Order Information
	ÄKTApurifier™ ÄKTApurifier core systems, together with ÄKTAdesign automation kits and hardware, ensure that purification efforts are always focused on target proteins of interest. Purification can be performed at microgram, milligram or gram scale, depending on the core system and kits selected. All this translates into improved versatility and tailor-made solutions for a specific application workflow of interest. Product and Order Information
	ÄKTAprime™ plus ÄKTAprime plus is a compact one-step purification system that operates with most prepacked columns, like HiTrap™, HiPrep™ or HiLoad™. The system has preprogrammed methods for typical applications such as purification of affinity tagged proteins, antibodies and sample clean-up. At the touch of a button you have your purifications running. Product and Order Information
	ÄKTAexplorer™ ÄKTAexplorer is the classic system for method development, designed for scouting, development, and optimization of methods for all chromatographic techniques. Product and Order Information
	ÄKTAprocess™ ÄKTAprocess is an automated liquid chromatography system built for process scale-up and large-scale biopharmaceutical manufacturing. The proven design has been verified during development and can be userconfigured to meet specific process demands. ÄKTAprocess is the obvious choice of system to use when scaling up processes developed on smaller ÄKTAexplorer™ and ÄKTApilot™ systems. Product and Order Information
	ÄKTA™ready ÄKTA ready is a liquid chromatography system built for process scale-up and production for early clinical phases. The system operates with ready-to-use, disposable flow paths and as a consequence, cleaning between products/batches and validation of cleaning procedures is not required. Product and Order Information
	ÄKTAcrossflow™ The purification of biomolecules normally uses membrane separations to concentrate and wash feed prior to chromatography. ÄKTAcrossflow™ is a fully automated system for cross flow filtration (ultrafiltration/diafiltration and cell separation) designed for process development and optimization. Product and Order Information
	ÄKTApilot™ ÄKTApilot is a benchtop process development and production system. The hygienic design, high level of automation, accuracy, reproducibility and reliable operation make ÄKTApilot the perfect system for scale up, process optimization and production. The design gives a smooth path to the cGMP workflow Product and Order Information
	ÄKTA™oligopilot™ plus ÄKTA oligopilot plus is a flexible and fully automated DNA/RNA oligonucleotide synthesizer designed for use in research, process development laboratories, and production. ÄKTA oligopilot plus is designed to meet the needs of new synthesis chemistries like RNAi and enables cost-efficient and high-quality synthesis. Product and Order Information

UNICORN™ - For fast and efficient control of protein purification

UNICORN protein purification software is used by more than 50,000 people in more than a thousand manufacturing installations worldwide. Our software is able to generate high-quality purification results due to its flexible and intuitive method concept supported by advanced tools for result assessment.
UNICORN control system enables real-time control of ÄKTAdesign chromatography systems in basically any scale, from laboratory bench, through development, to full-scale production. The Method Wizard provides easy method generation, and extensive data evaluation can be done using automated Evaluation Procedures.

Features and benefits Intuitive design and easy to use Flexible and powerful purification method development
Fast and cost-efficient method optimization scouting and scale-up Advanced result assessment for chromatography and filtration Reliable and robust control concept Support for regulatory compliance (including 21 CFR part 11) Cost-efficient integration to other systems with OPC Simplified and automated column packing One common platform for filtration and chromatography The UNICORN software solution is continuously being developed to maintain its position as one of the leading solutions for protein purification worldwide. GAMP4 documentation is offered as an option.

UNICORN in the laboratory offers

• Full control of user access, systems and data
• Share systems and data in a network according to your set access profiles.
• Real-time overview of the system and display of actual system status.
• The Method Wizard allows simple control of your protein purification methods with the most recent types of media.
• Simple transition
  - Remain flexible in the clinical manufacturing environment with optional UNICORN control integrated via UNICORN general OPC support.
  - Easy transfer of developed chromatography and filtration methods from the lab systems to the manufacturing systems.
  - No need for user training in new environments.
  - Use Scouting to automate screening for optimal purification conditions.
  - Conditional control functions for real time optimization of purification methods.
  - Evaluate results with analytical tools for quantization, molecular weight determination and recovery.

UNICORN in manufacturing offers

• Efficient and reliable purification methods for chromatography and filtration:
• Stay updated with column and media specs with data from the column list.
• Automatically evaluate and present purification results in reports with your own design or on predefined templates.
• Expand the systems configuration with built in capabilities for optional hardware.
• Store generated data to batch historian via OPC.
• Conforms to current US FDA guidelines and regulations.
• Intelligent Packing with AxiChrom™ columns.
  
  
  

Instrument Maintenance Agreements with Labcrew™

Ensure the maximum performance of your GE Healthcare Life Sciences instrument system with Service Agreements and Preventive Maintenance.A Service Agreement for your instument system helps to maintain long-term performance and to insure your investment against any unexpected breakdown costs. Learn more in the Service area.

Fast Trak Training & Education Get the training you need in chromatography, process development, column packing, filtration or cell culture with Wave™. Fast Trak Training & Education has over 20 years of experience that provide you with the skills and knowledge for your industrial bioprocessing. Our online training courses help you exploit the capabilities of ÄKTA™ protein purification systems with ease and full control. Complete the training at your own pace. The courses are structured in logical modules and accessible for one year. The UNICORN™ 6 eCourse (eSYS6) handles UNICORN 6 control software for the ÄKTA avant system. Other UNICORN versions are covered in the Online Basic Training Course for UNICORN (eSYS1),with eSYS1 exercises taken from ÄKTApurifier™ and ÄKTAexplorer™, although the course is also relevant for ÄKTApilot™, ÄKTAfplc™ and ÄKTAmicro™ users. GE provides training for a wide range of other application areas. Contact your local representative at GE Healthcare Life Sciences for further information.

Direct answers to laboratory and process-scale chromatography questions

Keep your research results coming in and your process operations on track. We've gathered our chromatography technical support on one single portal. The result will minimze the time you spend chasing answers to questions about spare parts and accessories, materials, packing and testing methods and many similar topics. Quickly find what you're looking for on Chromatography online support.