ÄKTAcrossflow™ - Putting the "brain" into membrane screening

ÄKTAcrossflow™ is a fully automated filtration system for cross flow membrane screening, process development and small scale processing. It’s also the first system to enable automation at very small scale, with capacity ranging from liters down to 25 ml.
Automation gives you complete mastery of your process at the touch of a button, making it astonishingly fast and easy from beginning to end. Intelligent UNICORN™ control software saves you days of data evaluation time. It even lets you integrate your cross flow filtration and chromatography processes, controlling everything from a single PC.
With ÄKTAcrossflow simple, cost-effective screening and process development are no longer pure imagination.

Features and benefits

Eliminate operator errors in cross flow filtration to ensuremore reliable results

Evaluate data automatically in hours rather than days

Seamlessly integrate your cross flow filtration and chromatography processes

Work with sample volumes from liters down to 25 ml

Ensure minimal disruption of proteins and cells due to innovative design

Technical specification

Operating range

Feed flow rate	1-600 ml/min
Transfer flow rate	0.1-200 ml/min
Permeate flow rate	0.1-200 ml/min
Max. system pressure	5.2 bar (75.4 psi)
Min. recirculation volume	< 25 ml

Detection and control

Pressure transducers	< ± 0.01 bar (0.15 psi)
TMP control accuracy	< ± 0.05 bar (0.73 psi)
Flow rate and displaced volume transfer and permeate pump	± 0.5% within 2 - 200 ml/min
feed pump	< ± 2.0% within 2 - 600 ml/min
Dimentions	620 × 400 × 650 mm
Weight	70 kg
Operating temp.	4-40°C, 50°C at membrane cleaning

Literature

Application note

Automated microfiltration using ÄKTAcrossflow pdf

Automated ultra filtration of IgG4 with ÄKTAcrossflow pdf

Brochure

ÄKTAcrossflow - Putting the brain into membrane screening pdf

Data file

ÄKTAcrossflow - automated cross flow filtration for process development pdf

Selection guide

Prepacked chromatography columns for ÄKTAdesign and Ettan LC systems pdf

User Manual

ÄKTAcrossflow pdf

Instrument Maintenance Agreements with Labcrew™

Ensure the maximum performance of your GE Healthcare Life Sciences instrument system with Service Agreements and Preventive Maintenance.A Service Agreement for your instument system helps to maintain long-term performance and to insure your investment against any unexpected breakdown costs. Learn more in the Service area.

Fast Trak™ Training & Education

Get the training you need in chromatography, process development, column packing, filtration or cell culture with Wave™. Fast Trak Training & Education has over 20 years of experience that provide you with the skills and knowledge for your industrial bioprocessing.

GE also provides training for a wide range of other application areas. Contact your local representative at GE Healthcare Life Sciences for further information.