Biacore™ systems for label-free interaction analysis

Biacore systems enable the measurement and characterization of almost any type of biomolecular interaction without the need for labels, providing high-quality data on binding affinity, kinetics and specificity, as well as concentration measurements based on specific binding activity. Real-time, label-free detection of interactions is provided by surface plasmon resonance (SPR), which measures changes in mass concentration close to a sensor surface.

Biacore systems are used in areas such as pharmaceutical drug discovery, antibody characterization, immunogenicity, biotherapeutic development and manufacture, and throughout life science research. Key applications include:

• Quantification of binding affinity & kinetics
• Determination of binding specificity and number of binding sites
• Characterization of mechanism of action
• Confirmation of biomolecule binding to target
• Screening of fragment libraries
• Validation of IC50/EC50 values during hit-to-lead
• Characterization of immune responses

A range of systems is available to meet specific application needs, along with a full range of consumables (sensor chips, application-focused reagent kits etc) and backed by expert support based on decades of knowledge and experience. Visit the Biacore web site for more details.