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Protein Purification
Overview
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Tagged protein purification
Antibody purification
General protein purification
Chromatography techniques
Affinity
Chromatofocusing
Gel Filtration & Desalting
Hydrophobic Interaction
Ion Exchange
Reversed Phase
Chromatography columns
Prepacked columns
Empty columns
Customized columns
Chromatography systems
Filtration
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Chromatography systems

ÄKTA™ is a Swedish word that means true, genuine, or real. ÄKTA design is the name for a platform of systems that help you make real advances in biomolecular purification and separation. By more than 100 000 scientists worldwide – purifying proteins for structural or functional studies, developing protocols, and optimizing methods for biomolecule purification – the name ÄKTA has always meant outstanding protein purification. This proud lineage now sky rockets into the next generation with ÄKTA avant. ÄKTA avant is the fastest, most secure means to develop scalable and robust chromatographic processes for biopharmaceutical production.

ÄKTA systems work with intelligent, scalable UNICORN™ software, which makes it simple to control every stage and scale of your purification process. GE Healthcare also offers an extensive range of prepacked columns, chromatography media, and filters to increase productivity and obtain optimal results.

With the ability to purify virtually 100% of all biomolecules, the ÄKTA design platform can handle the simplest and the toughest of challenges. It gives you speed, ease-of-use, and flexibility whatever your purification application or scale. Our interactive
ÄKTA systems selection guide is a practical tool that helps you to select the right system for your purification needs.


ÄKTA systems - Ability to purify virtually 100% of all biomolecules



ÄKTA™ avant
ÄKTA avant 25 is a preparative liquid chromatography system intended for media screening, method scouting, and process development. UNICORN™ 6 control software has been specially developed for ÄKTA avant to increase productivity and efficiency. The ÄKTA avant system offers a complete solution for fast and secure process development.

Product and Order Information



Ettan™  LC  Product and Order Information
ÄKTAmicro™
ÄKTAmicro system is developed from the ÄKTA design chromatography platform utilizing inert, biocompatible flow paths with minimized dead volumes to limit sample dilution, ensure high sample recovery, top resolution, and high sensitivity during micropurification. The system is also an excellent choice for fast purity analysis by gel filtration in method development and for drug target characterization.

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ÄKTAxpress™ Product and Order information
ÄKTAxpress™
ÄKTAxpress performs unattended purification of antibodies and affinity tagged proteins and hence saves time in the lab. This system produce highest possible purity of target proteins allowing, for example, structural and functional studies to be easily performed up-stream. Optimized protocols with a choice of up to four different purification steps makes it easy to use with minimial or no need for chromatography expertise.

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ÄKTApurifier™ Product and Order information
ÄKTApurifier™
ÄKTApurifier core systems, together with ÄKTAdesign automation kits and hardware, ensure that purification efforts are always focused on target proteins of interest. Purification can be performed at microgram, milligram or gram scale, depending on the core system and kits selected. All this translates into improved versatility and tailor-made solutions for a specific application workflow of interest.

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ÄKTAprime™ plus Product and Order Information
ÄKTAprime™ plus
ÄKTAprime plus is a compact one-step purification system that operates with most prepacked columns, like HiTrap™, HiPrep™ or HiLoad™. The system has preprogrammed methods for typical applications such as purification of affinity tagged proteins, antibodies and sample clean-up. At the touch of a button you have your purifications running.

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ÄKTAexplorer™ Product and Order information
ÄKTAexplorer™
ÄKTAexplorer is the classic system for method development, designed for scouting, development, and optimization of methods for all chromatographic techniques.

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ÄKTAprocess™ Product and Order information
ÄKTAprocess™
ÄKTAprocess is an automated liquid chromatography system built for process scale-up and large-scale biopharmaceutical manufacturing. The proven design has been verified during development and can be userconfigured to meet specific process demands. ÄKTAprocess is the obvious choice of system to use when scaling up processes developed on smaller ÄKTAexplorer™ and ÄKTApilot™ systems.

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ÄKTA™ready   Product and Order Information
ÄKTA™ready
ÄKTA ready is a liquid chromatography system built for process scale-up and production for early clinical phases. The system operates with ready-to-use, disposable flow paths and as a consequence, cleaning between products/batches and validation of cleaning procedures is not required.

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ÄKTAcrossflow™ Product and Order Information
ÄKTAcrossflow™
The purification of biomolecules normally uses membrane separations to concentrate and wash feed prior to chromatography. ÄKTAcrossflow™ is a fully automated system for cross flow filtration (ultrafiltration/diafiltration and cell separation) designed for process development and optimization.

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ÄKTApilot™ Product and Order Information
ÄKTApilot™
ÄKTApilot is a benchtop process development and production system. The hygienic design, high level of automation, accuracy, reproducibility and reliable operation make ÄKTApilot the perfect system for scale up, process optimization and production. The design gives a smooth path to the cGMP workflow

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ÄKTA™ oligopilot plus Product and Order Information
ÄKTA™oligopilot™ plus
ÄKTA oligopilot plus is a flexible and fully automated DNA/RNA oligonucleotide synthesizer designed for use in research, process development laboratories, and production. ÄKTA oligopilot plus is designed to meet the needs of new synthesis chemistries like RNAi and enables cost-efficient and high-quality synthesis.

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