Protein Analysis
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Over the decades, we have been involved in several significant developments in protein science ranging from chromatography and electrophoresis-based methods to quantitative imaging. We have pioneered the world’s first electrophoresis system, the first surface plasmon resonance (SPR) system for label-free protein interaction studies, and the first chemiluminescent reagents for Western blotting. These detection systems are the still widely used today.
Proteomics is considered the next step in the study of biological systems after genomics. It is more complicated than genomics, because while an organism's genome is more or less constant, the proteome differs from cell to cell and over time. Not only does translation from mRNA lead to differences, many proteins are also subjected to a wide variety of post-translational modifications (PTM) critical to their function. Different approaches are available for proteomic studies depending on your final goal, the source of your sample, as well as availability of tools and material. 2-D electrophoresis is a helpful tool to study the proteome, especially 2-D Fluorescence Difference Gel Electrophoresis (2-D DIGE). Protein-specific antibodies allow you to detect protein targets in a complex sample using Western blotting or ELISA. When suitable antibodies are not available, Far Western blotting, surface plasmon resonance (SPR), or microcalorimetry can be used to identify proteins.
From electrophoresis and blotting to labeling, detection and quantitative imaging, we provide a range of products to fit your application needs
Whether you’re analyzing protein expression in proteomics or for specific proteins, we can provide solutions to suit your needs.
To fully understand how proteins work, study their interactions as well as their biophysical properties
The potential for precise, truly quantitative protein analysis is steadily increasing with a broad spectrum of technologies now available
Defining the thermodynamic forces that drive folding and unfolding help make it easier to understand and predict protein behavior
