Label-Free Analysis Technologies
We offer a range of systems, accessories, and reagents for label-free analysis using microcalorimetry or surface plasmon resonance (SPR). These techniques provide information-rich, real time data without the use of labels. In areas as diverse as basic research, drug discovery research, process development and quality control (QC), microcalorimetry and SPR allow you to draw confident conclusions about biomolecular interactions enabling more confident decision making.
Label-free interaction analysis is of increasing importance in the academic, pharmaceutical, and biotechnology markets. Label-free analysis enables the comprehensive characterization of biomolecular interactions and complex stability.
SPR and microcalorimetry detect the formation and dissociation of molecular complexes by changes in mass or heat, respectively. The information-rich data enable key insights into biological processes and molecular binding mechanisms. These technologies meet the needs of fields as diverse as biological research, biotherapeutic and small molecule drug development research, immunogenicity studies and vaccine development, and QC.
Microcalorimetry measures the direct heat change associated with molecular interactions and other biochemical processes
Label-free molecular interaction analysis using SPR provides quantitative data on specificity, concentration, kinetics, and affinity