Our MegaBACE sequencers save time through automated gel matrix replacement, sample injection, electrophoresis, and data analysis. We support our MegaBACE product range of automated capillary sequencers with consumables. We also offer reagents to support ALFexpress and some ABI automated sequencers.
The development of automated DNA sequencing has greatly expanded the scope of DNA sequencing. Based on chain-termination, fully automated Sanger sequencing instruments involve separation of fluorescently labeled terminated fragments by electrophoresis in slab gels or capillaries and detection of dye fluorescence.
Automated sequencing is a powerful approach to applications where throughput is critical, such as genomic sequencing and large-scale genotyping studies. Large numbers of reactions can be processed simultaneously followed by rapid read-out of nucleotide sequences.