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    Webinar: Principles of immunogenicity assessment using Biacore T200

    Enjoy the free, on-demand webinar.

    VIEW WEBINAR

    Make the switch from ELISA
    to Biacore SPR-based assays

    Read more on how to save three hours in determination of active protein concentrations.

    READ ARTICLE

    Better comparability, release testing and impurity monitoring

    Don’t miss out of our free on-demand presentation
    “Novel analytics to improve bioprocessing and validation guideline review”.

    VIEW PRESENTATION

    Robust analytical control strategy with information-rich technologies

    Therapeutic proteins, monoclonal antibodies (mAbs), bispecific antibodies, and antibody-drug conjugates are all large complex molecules that require robust and reliable methods for analysis and in-depth characterization. GE Healthcare offers tools for analysis of protein size and purity, host cell protein (HCP) impurity, and drug potency and comparability. Our analysis tools each have the potential to significantly improve drug product characterization and quality control to increase productivity.

    NEW! Read latest article: Optimizing drug safety and efficacy of complex next-generation biologics.

    Free download of latest poster booklet

    Read more about:

    • Quantitation of aggregates and/or protein fragments
    • Surrogate potency assays with SPR—two CQA determined in only one assay
    • Facilitating IgG FcRn analyses
    • Reliable HCP detection
    DOWNLOAD

    Ensure SEC column reproducibility in protein drug analysis

    Size exclusion chromatography (SEC) is the most powerful chromatography technique for reliable information and studies of molecular size, antibody aggregation, and truncation even under native conditions.

    LEARN MORE

    How well are your HCP ELISA tests covered?

    Validating host cell protein ELISAs is an essential part of biologics development. But what makes these coverage assays so vital, and what could we improve? Read the blog to see how our 2D DIBE approach combines the best of existing methods.

    READ BLOG

    Sensitive and reproducible SPR-based concentration and ligand-binding analyses

    Ligand-binding assays are key for characterization of biotherapeutic medicines. Biacore systems and ligand-binding assays are based on surface plasmon resonance, (SPR) technology and have been used for antibody characterization and quantitation for more than 20 yr.

    Regional seminars and workshops

    Join us in 2019 in a location near you to discover exciting new research and applications while networking with peers from academia and industry.

    • Biacore User Day | Cambridge, MA, U.S.A | October 1
    • HCP Forum | Stevenage, UK | October 3
    • Biacore Academy | Giessen, Germany | October 8-11
    • Innovations in Protein Research | San Diego, CA, U.S.A. | October 22
    • Biacore User Day | San Francisco, CA, U.S.A. | October 28
    • Biacore Academy | Barcelona, Spain | October 29-30
    • Paris, France | November 27-28 – Registration coming soon
    • Philadelphia, PA, U.S.A. | December 12 – Registration coming soon
    A new magnifying glass for CQA monitoring

    A new magnifying glass for CQA monitoring

    Ligand binding for assessment of similarity and relative potency

    Ligand binding for assessment of similarity and relative potency

    SPR for biopharmaceutical drug release and stability

    SPR for biopharmaceutical drug release and stability

    Related content

    • Article – Optimizing drug safety and efficacy of complex next-generation biologics
    • Article – Process effects on drug product quality in pharmaceutical manufacturing—a validated measurement process
    • Article – Ensure SEC column reproducibility in protein drug analysis
    • Blog post – How well are your HCP ELISAs covered?
    • Article – Sensitive and reproducible SPR-based concentration and ligand-binding analyses
    • Article - Converting from ELISA to Biacore SPR assays
    • Blog post – Why, why, why… ELISA? A look at the benchmark HCP assay
    • Article – Enhanced host cell protein analysis in biologics manufacturing
    • Handbook – Biacore Assay
    • Handbook – Biacore Sensor Surface
    • Handbook – Size Exclusion Chromatography Principles and Methods
    • Handbook – Imaging Principles and Methods
    • Handbook – Western Blotting

    Related products

    • Biacore 8K SPR system
    • Biacore 8K+ SPR system
    • Biacore T200
    • HCP Quant CHO host cell protein ELISA kit
    • Amersham Typhoon gel and blot imaging system
    • Melanie Coverage software
    • Argentina
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