MabSelect PrismA affinity chromatography resin has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein A-derived ligand. This allows future demands in mAb purification to be met, including processing of many bispecific antibodies.
- Enhanced dynamic binding capacity allows high mass throughput of processed mAb per resin volume unit.
- Excellent alkaline stability enables efficient cleaning and sanitization using 0.5–1.0 M NaOH for improved process economy, bioburden control, and robustness.
- Covered by a comprehensive security of supply program, including dual sources of the agarose base matrix and protein A ligand.
The enhanced alkaline stability of MabSelect PrismA also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bioburden control for continuous processes, which can be exposed to days or weeks of feed harvest.
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Product | Product Name | Price | |
---|---|---|---|
17549801 | MabSelect PrismA, 25 mL | 2 035.00 EUR | Add to cart |
17549802 | MabSelect PrismA, 200 mL | 5 621.00 EUR | Add to cart |
17549803 | MabSelect PrismA, 1 L | On Request | Get Quote |
17549804 | MabSelect PrismA, 5 L | On Request | Get Quote |
17549805 | MabSelect PrismA, 10 L | On Request | Get Quote |
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