Biacore 8K+ is a high-throughput, high-sensitivity SPR system, which delivers binding data of outstanding quality with maximized capacity. Biacore 8K+ is designed to meet your toughest challenges in screening, characterization, process optimization, and quality control.
- Single solution for interaction analysis allowing ranking, kinetics, affinity, concentration, and relative potency.
- Screening of 2300 molecules in a day.
- High-quality kinetic characterization of 64 interactions in 4 h.
- Exceptional sample capacity of up to 12 × 384-well microplates.
- 72 h unattended run time with queueing abilities and rapid multirun evaluation.
Performance to meet the toughest applications
Biacore 8K+ eight needle, high-sensitivity SPR system allows the measurement of 16 interactions to rapidly provide kinetics and affinity data. The high capacity effectively shortens time to results up to eight times compared to single-needle systems. The blend of instrument flexibility and throughput provided by both systems reduces the experimental cycle time, even for complex targets and for new drug formats such as bispecific antibodies.
The system gives you a single solution for interaction analysis in both screening and characterization and is well suited to the analysis of samples from the smallest fragments to large multidomain proteins, even in crude matrices.
Outstanding sample capacity
The sample hotel of Biacore 8K+ accommodates up to six trays. Each tray can hold two microplates, which translates to a maximum unattended run capacity of 4608 samples.
Concentration and potency analyses without compromising data quality
The system is equipped with tools to allow efficient concentration determination regardless of sample size, running samples in parallel to minimize time to results. Biacore Insight Evaluation Software provides concentration evaluation functionality, available as an add-on extension package with dedicated software tools for concentration and potency analysis and parallel line analysis (PLA).
When regulatory compliance is required
Biacore Insight Evaluation Software GxP Extension package is a software add-on enabling the use of the system in regulated applications. The GxP Extension package facilitates compliance with worldwide regulatory expectations.Read less
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