Knowledge Center

The antibody boom

Antibodies continue to dominate the biopharma market. Analyzing the strategies employed by successful players in the field could provide invaluable lessons for those hoping to enter it.

The good and bad of biosimilars

The biosimilars market is suddenly booming, with established biopharma giants and nimble start-ups all clamoring for a piece of the action. But such steep competition means that only the wise will survive.

Vaccines: A balancing act

Although absolutely crucial for maintaining global health, vaccines are challenging to develop and manufacture. How can businesses ensure profitability while maintaining low prices for developing countries?

Biopharma: How to win in emerging markets

Unexplored and emerging markets are an attractive prospect for biopharma companies looking to expand. But when it comes to ensuring success, what’s the wisest way to invest?

Amgen: Linking raw material data from suppliers to patients

By collaborating openly across the industry, we can minimize and control raw material risk and better manage our supply chain for the purpose of delivering the safest and most effective drugs possible.

Antibody fragments

Purify scFvs dAbs, and Fabs efficiently with platform-enabling technologies

Bacterial capsular polysaccharides

Purification platform for vaccine production

Bioburden control

Addressing microbial contamination

Biopharma: Addressing talent crunch in a growing industry

Gaining a skilled labor force in the growing biopharma industry can be a challenge. So what strategies should your company be considering for recruiting, training and retaining qualified bioprocessing candidates.

Bioreactor oxygen

Importance of aeration and ways to control kLa during cell cultivation

Can a shared biomanufacturing facility be the answer?

With a shared biomanufacturing facility, you can mitigate the risks of demand uncertainty using a flexible solution that allows you to grow and change in the new paradigm of biomanufacturing.

CDMO or no CDMO . . . that is the question

By checking the pulse of your organization first, it is possible to identify gaps and develop a plan for how to address them, so you can make the right decisions at the right time.

Cell culture titer and protein quality

How media composition can maximize protein yield and quality attributes

Concentrated fed-batch

Intensify your process by going from cell vial to 2000 L bioreactor in 1 step

Continuous chromatography

PCC chromatography + straight-through processing = intensified

Digital aids productivity and growth

Digital technologies can improve productivity and growth in cell therapy manufacturing and in bioprocessing.

Digital manufacturing of biologics

The recent explosion in monitoring, analytics and new computing capabilities initiated the revolution called digital biomanufacturing. Learn how it can help biomanufacturers to improve their manufacturing processes.

Digital transformation in biomanufacturing

Industry 4.0 uses digital connection and advanced analytics to improve bioprocess productivity. Digital transformation is how to get there. A GE and Biogen case study illustrates the value.

Doubling up for speed in biomanufacturing

Parallel operations affords the opportunity to develop a process in a parallel path using the resources of an external CDMO partner while simultaneously establishing your manufacturing capabilities.

Fermentation

Which offers better process economy and production capacity: single-use or stainless?

Filtration

How to efficiently concentrate a low-titer antibody sample

Flavivirus vaccine

Accelerate production with modern tools and solutions

Gain efficiency in process development

Learn how fellow scientists use ÄKTA avant to gain efficiency in protein purification process development

Integrating automation in a biomanufacturing environment

Integrating automation can become a daunting task without the right preparation and a clear implementation strategy. Through proper planning, you can eliminate costly errors and missteps. 

Influenza vaccine

Production process using single-use bioprocessing equipment

Manufacturing of viral vectors

For use in gene therapy and development of therapeutic vaccines

Monoclonal antibodies

Intensify downstream processing of mAbs with innovative, integrated approaches

Next generation bioprocesses: Mapping roads to the future

Explore available options to select a path based on molecule and facility needs

Preparing for the future of biomanufacturing

New market dynamics are reshaping how biologics are produced and sold. Here’s what six industry experts say about the way forward.

Resin slurry concentration

Accurate determination for optimal column performance

Single-use chromatography

Adapting to manufacturing scale

Suppliers' contributions to bioprocessing advances

From platform processes to disruptive technologies: The future of innovation continues.

The transparent CDMO

Handing over vital information about your product can be very unnerving. That is why it is important to find a CDMO who can help alleviate drug development risks and protect your intellectual property (IP).

Vaccines

Accelerate cell-based vaccine production with modern tools and solutions

Bioprocess filtration

Calculators and converters for tangential and normal flow filtration

Chromatography

Calculators, converters, and selection guides for chromatography

Technical handbooks

Principles and methodology handbooks covering bioprocess techniques and applications

Automation solutions

Automation in process development and biomanufacturing

Single-use – impact on operations

Shire and GE discuss impacts and propose solutions for successful MES implementation

Risk management

Sustainable supply and risk management programs: challenges and considerations

5 key considerations for creating cGMP single-use biomanufacturing capacity

500 L single-use Xcellerex microbial fermentor

Fortem single-use platform film built for bioprocessing

KUBio: The proven response for rapid biomanufacturing

ReadyToProcess prepacked, validated columns

Rehydrating powder media with Xcellerex mixers

Single-use TFF system: ÄKTA readyflux

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