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A robust workflow that can be adapted for cGMP compliance in commercial production. Achieves 1 × 1010 expanded T cells in 8 days.
Upstream lentiviral vector process with stable producer cell line that can be adapted for commercial manufacturing. Scales linearly from 5 to 28 L in Xcellerex bioreactors yielding ≥ 1010 TU/L of LV-GFP.
Two cell therapy experts provide practical advice on when and how to start thinking about compliance with good manufacturing practices (GMP).
This study was designed to answer the question: When is it safe to transfer cell samples from a controlled-rate freezer to liquid nitrogen storage?
This study shows comparable results when freezing cells with or without a rapid-cooling nucleation step.
Customer study shows reproducible cord blood freezing without liquid nitrogen.
Read about this benchmarking study and benefits of dry thawing technology.
Expand your knowledge on perfusion, our rocking technology and more by reading through our latest papers and posters.
Workflow for NK cell production from apheresis units. Isolation, xeno-free expansion, harvest, and cryopreservation amenable to GMP manufacturing.
CBMG accelerates cell therapy manufacturing with GE Healthcare’s start-to-finish FlexFactory for cellular therapies.
How does a power interruption during cooling affect post-thaw cell viability? This study demonstrates minimal effect of power outages and interrupted cooling during cryopreservation when using a VIA Freeze controlled-rate freezer.
Overcoming the challenges of manufacturing and administering a complex product to any patient is critical for delivering cell therapies. Here two industry experts provide practical advice on strategies to meet supply chain challenges.
A proof-of-concept study that demonstrates the controlled cooling of large volume biological samples with high and consistent post-thaw recovery. An alternative solution to cryopreserving with liquid nitrogen.
Cooling protocol and proof-of-concept study for the cryopreservation of large-volume biological samples in cryovials. Achieve high and consistent post-thaw recovery of up to 50 mL in this liquid nitrogen-free cell freezing method.
Customer case study describes a robust upstream process and downstream process for oncolytic adenovirus production. Purity of final samples meets regulatory requirements.
For cell and gene therapies, the supply chain and logistics are critical. Collaboration is the key to solving data management and process variability challenges.
Development of a scalable process to produce high-yield lentiviral vector batches using stable, suspension-based production methods.
Calculating working volumes for your Percoll solutions is now easier. Download it to your preferred device or use the web app.
Visit our collection of videos to learn more about GE cell therapy technologies.
